We are part of the Department of Genetics and Genomics Sciences and a member of the Institute for Genomics and Multiscale Biology at the Icahn School of Medicine at Mount Sinai (ISMMS). While we are broadly interested in Bioinformatics/Computational Biology research topics, the primary research focus for the lab is problems related to genomic architecture. In the past these problems have ranged from phylogenetics to detecting rearrangements and gene fusions in human cancers. Currently, some of these projects include pathogen genome assembly/comparison, human structural variation/phasing, and transcriptomics. Together with our collaborators, we use whatever technologies are available but have specifically made use of the significant advances in genome sequencing made in the last few years.
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