We are working with Ravi Sachidanandam and his group of computational biologists to better understand how gene expression, and microRNAs in particular, are regulated.
Our group is working closely with Miriam Merad and her lab to uncover the regulatory networks that control dendritic cell and macrophage biology. This includes our work together as part of the Immgen consortium (below).
We are collaborating with Emily Bernstein and her lab to try and understand how microRNAs and chromatin regulators control cancer cell behavior.
In collaboration with Matthew Evans, we are studying the regulatory interactions between hepatitis C virus and host cell microRNAs.
We are members of the Immgen Consortium, an NIH funded project led by Dr. Christoph Benoist, whose goal is to determine the complex molecular networks that control and connect all cells in the immune system. The Immgen Consortium has already profiled more than 200 different cell types of the immune system, and made the data available to the public, in a highly accessible format.