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Chess Lab


Andrew Chess MD

Icahn School of Medicine at Mount Sinai

Annenberg Building, 25th Floor, Room 62B

1468 Madison Avenue

New York, NY 10029



Tel: 212-241-9695

We are interested in unusual mechanisms involved in regulating gene expression. Recently, we have been developing approaches to studying epigenetic regulation at the scale of the entire human genome. Elucidation of epigenetic mechanisms is essential to normal development and disease. Some of our recent discoveries may help in elucidating complex heritable disorders.

Are there yet uncovered mechanisms impacting gene regulation which can be discovered through genome-scale approaches?

What gives individual cells their identities?

How unique are individual cells?

These questions (and others) have been approached in studies of various species including Humans, mice and the fruit fly, Drosophila melanogaster.

Further information can be found here.

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Andrew Chess is a Professor in the Department of Cell, Developmental and Regenerative Biology, the Department of Neuroscience, and the Department of Genetics and Genomic Sciences. Our lab is also part of the Icahn Institute for Genomics and Multiscale Biology and the Friedman Brain Institute. The lab is located on the 25th floor of the Annenberg Research Building.