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Dendritic Spine Detection

The spine detection and classification module of NeuronStudio allows you to find and classify spines in a dataset after a model has been traced or imported. Select Run >> Build Spines to begin this procedure. A progress window will appear at the top of the display window. Hitting the cancel button of this progress window will terminate the detection and classification. All detected spines are classified according to the currently selected classification scheme. For more information on spine classification please refer to the Spine Classification section of this guide.

IMPORTANT: Check that the parameters in the settings window are correct.

TIP: Pressing the S key as a shortcut is a faster way to begin spine analysis.

The image below shows a dendritic segment before spine detection and classification.

Before Spine Detection

The image below shows the same dendritic segment after spine detection and classification.

After Spine Detection

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Send questions or comments to: alfredo.rodriguez@mssm.edu