Pilot Project

Rashmi N. Aurora
Rashmi N. Aurora, MD
Assistant Professor Medicine, Pulmonary, Critical Care and Sleep Medicine
Mount Sinai School of Medicine

Obstructive Sleep Apnea Syndrome and Pre-Diabetes in East Harlem: a pilot study to assess the feasibility of portable sleep apnea monitoring and prevalence of sleep apnea in individuals with pre-diabetes

Obstructive sleep apnea syndrome and type 2 diabetes are two conditions strongly associated with obesity that have grown in tandem with the obesity epidemic. These two conditions are not only linked as a consequence of obesity as emerging evidence suggests that sleep apnea is an independent risk factor for the development of glucose dysregulation. It follows that early recognition and treatment of sleep apnea may play a role in diabetes prevention. Diagnostic testing for sleep apnea has typically involved a resource-intensive, costly, and burdensome in-laboratory overnight sleep study – polysomnography. Portable sleep apnea monitoring devices are available and provide a convenient and cost-effective approach to diagnosing sleep disordered breathing. There is a significant void in the current literature as it pertains to assessing home monitoring strategies in minority and underserved populations with pre-diabetes.

There is now a tremendous opportunity to integrate basic science, clinical, and community-based research on diabetes prevention and sleep apnea in minority communities, furthering both fields and providing benefit to local communities. Project HEED is an NIH-funded, community based participatory research study in which peer lead lifestyle intervention is offered to overweight/obese individuals (primarily Black and Latino populations) with pre-diabetes in East Harlem. The aims of this study are:

  1. To assess the feasibility of in-home, portable sleep apnea monitoring in an underserved, minority population.

  2. To determine the prevalence and severity of OSAS, a potential risk factor for diabetes, in an underserved, minority population with impaired glucose metabolism as indexed by oxygen desaturation and the AHI.

Specifically, we propose to develop a system of offering home-based screening for sleep apnea to adults with pre-diabetes and provide information and treatment as necessary in a culturally appropriate manner.