Our research focuses on the analysis of human genetic variation to address fundamental questions in biology, medicine and anthropology. We are interested in detecting patterns of demography in genomic data to inform our inference of human evolution and history, and result in better outcomes for medical genomics. We combine population genetics theory, complex disease mapping, statistical modeling and experimentation to gain a deeper understanding of the landscape of genetic variation in global populations and its impact on function, fitness and adaptation. A detailed description of current projects can be found here.
2017.08.08: Mount Sinai selected as one of six national sites for the NHGRI funded Clinical Sequencing and Evidience-based Research; NHGRI Press release, PharmaBiz, GenomeWeb, Crain Business News , Healthcare IT News
2017.08.02: Medicine is getting more Precise... For White People on FiveThirtyEight
2017.07.06: Editors pick in American Journal of Human Genetics "Polygenic Risk Scores for the World"
2017.05.22: Comment in " In 'Enormous Success', Scientists Tie 52 Genes to Human Intelligence" in The New York Times
2017.04.17: "Patient Diversity in Cancer Research Essential to Addressing Health Disparities, Scientists Say" on GenomeWeb