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Our laboratory studies growth factor signaling pathways that have important roles in mouse embryonic development. In particular, our lab is interested in the general question of how biological specificity is acquired upon engagement of growth factor signaling. A major focus of our research is in craniofacial biology, where we seek to identify the pathways by which Platelet Derived Growth Factor (PDGF) and Fibroblast Growth Factor (FGF) signaling in multipotent neural crest cells regulate the development of the midface. We are also establishing the signaling pathways engaged by FGF signaling that govern the establishment of stem cell fates from the early embryo.

Our laboratory is in the Department of Developmental and Regenerative Biology, Icahn School of Medicine at Mt. Sinai, on the 25th Floor of the Annenberg Research Building (large black building on the left) overlooking Central Park.