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Our laboratory studies growth factor signaling pathways that have important roles in mouse embryonic development. In particular, our lab is interested in the general question of how biological specificity is acquired upon engagement of growth factor signaling. A major focus of our research is in craniofacial biology, where we seek to identify the pathways by which Platelet Derived Growth Factor (PDGF) and Fibroblast Growth Factor (FGF) signaling in multipotent neural crest cells regulate the development of the midface and palate. We are also establishing the signaling pathways that are engaged by FGF signaling that govern the establishment of extraembryonic stem cell fate as well as the differentiation of embryonic and epiblast stem cells.


Our laboratory is in the Department of Developmental and Regenerative Biology at the Icahn School of Medicine at Mt. Sinai, on the 25th Floor of the Annenberg Research Building (large black building on the left) overlooking Central Park.


Icahn
School of     Medicine at
Mount
Sinaihttp://www.mssm.edu