My first degrees were in Experimental Psychology, from the University of Oxford and University of London (UCL); my PhD was from the SGDP, Institute of Psychiatry, KCL. I am now primarily based in the Icahn School of Medicine at Mount Sinai, New York, as an Associate Professor within Psychiatry and Genetics and Genomic Sciences.
I am also jointly appointed in the Psychiatric & Neurodevelopmental Genetics Unit (PNGU) and Analytic and Translational Genetics Unit (ATGU), which are part of the Center for Human Genetic Research (CHGR) at Massachusetts General Hospital (MGH) in Boston. I am a Senior Associate Member of the Broad Institute of Harvard and MIT and actively involved in the genetics program of the Stanley Center for Psychiatric Research based there.
Our work focuses on developing statistical and computational tools for the design of genetic studies, the detection of gene variants influencing complex human traits and the dissection of these effects in the larger context of other genetic and environmental factors. In particular, we currently work on whole exome resequencing and whole genome association studies of bipolar disorder and schizophrenia and the development of computational tools for whole genome and exome genetic studies.