Human age as the consequence of combined force of the mighty nature and the way how we are genetically coded. As the main goal of our genetic code is
to construct us to reproduce, keeping us in good shape afterwards is never the intension.
Aging can be defined at molecular level by measuring various changes associated with aging, such as gene expression, DNA methylation, protein expressions, etc.
Having this comphrehensive molecular picture of human aging is important and can help biomarker discovery, systems modelings, cross-species comparison, and drug development.
People have proven in model organisms that lifespan can be extended by various perturbations.
It is unclear if any of these would work in human.
Our goal is to develop an in silico predictive model, which is testable in model organisms, so we can predict
if a treatment can work in human by applying the model to human aging data.