Associate Professor
Department of Pathology
Mount Sinai School of Medicine
One Gustave L. Levy Place
Phone:
(212)241-0468
E-mail: haishan.wu@mssm.edu
Journal
Publications:
[70]. Hai-Shan Wu, and Steven Dikman,
“Segmentation of glomerular basement membranes from electron microscopy images,”
Journal of Electron Microscopy, accepted.
[69]. Hai-Shan Wu, Liane Deligdisch, Maria Isabel Fiel, Thomas Schiano, and Joan Gil,
“Image segmentation of secondary septa in lungs,”
Journal of Imaging Science
& Technology, accepted.
[68]. Hai-Shan Wu, Jacinta Murray, Susan Morgello, Maria Isabel Fiel, Thomas Schiano, Tamara Kalir, Liane Deligdisch, & Joan Gil,
“Restoration of distorted color microscopic images from transverse chromatic aberration of imperfect lenses,”
Journal of Microscopy, accepted.
[67]. Hai-Shan Wu, M. Isabel Fiel, Thomas D. Schiano, Marie Ramer, David Burstein, and Joan Gil,
“Segmentation of textured cell images based on frequency analysis,”
IET Image Processing, accepted.
[66]. Hai-Shan Wu, Feng-Qian Wang, Yoel Smicun, and David Fishman,
“Recognition of Linear Stress Fibers Based on Hough Transform,”
Analytical and Quantitative Cytology and Histology, accepted.
[65]. S.-Q. Chen, J.-N. Chen, X.-H. Cai, G.-R. Chen, R.-S. Ge, H.-S. Wu, Z.-L. Lin, J. Lin,
“Perinatal exposure to di-(2-ethylhexyl) phthalate leads to restricted growth and delayed lung maturation in newborn rats,”
Journal of Perinatal Medicine, accepted.
[64]. Sonia Dutta, Feng-Qiang Wang, Hai-Shan Wu, Thayer J.
Mukherjee, David A. Fishman,
“The NF-κB and EGFR Pathways Mediate Lysophosphatidic Acid
(LPA)-induced VEGF Signaling and Cell Invasion in Epithelial Ovarian Cancer
(EOC),”
Gynecologic Oncology, submitted.
[63]. W. J. M. Mulder, M. E. Lobatto, S. Silvera, E. Vucic, C. Calcagno, V. Mani, K. Nicolay, M. Banciu, R. M. Schiffelers, L. van Bloois, H.-S. Wu, J. T. Fallon, J. H. Rudd, V. Fuster, E. A. Fisher, G. Storm, and Z. A. Fayad,
“A glucocorticoid-based nanomedicine as targeted anti-inflammatory treatment for atherosclerosis,”
Science
Translational Medicine, submitted.
[62].
Hai-Shan Wu, Steven Dikman, and Joan Gil,
“A semi-automatic algorithm for measurement of basement membrane thickness in kidneys in electron microscopy images,”
Computer Methods and Programs in Biomedicine, vol.97, pp.223–231, 2010 .
[61]. Marie Ramer,
Hai-Shan Wu, Yael Ramer, Lurmag Orta, Patrick Emanuel, David E. Burstein,
“Prognostic value of quantitative p63 immunostaining in adenoid cystic carcinoma (ACC) of salivary gland assessed by computerized image analysis,”
Cancer,
vol.116, pp. 77-83, Jan. 2010.
[60]. M. Isabel Fiel, Hai-Shan Wu, Kishore Iyer, Gonzalo Rodriguez-Laiz, Thomas D. Schiano,
“Rapid Reversal of Parenteral Nutrition-Associated Cirrhosis Following Isolated Intestinal Transplantation,” Journal of Gastrointestinal Surgery, vol.13, pp.1717–1723, Sept. 2009.
[59]. Hai-Shan Wu, Mireille Bitar, David Burstein, Marie Ramer, and Joan Gil,
“An envelope mapping algorithm and its applications in enhancement and segmentation of pancreatic cell images,”
Journal of Imaging Science & Technology, vol.53, No.3, pp.030501-030501-6, May/June, 2009.
[58]. Hai-Shan Wu, Jacinta.Murray, and Susan Morgello,
“ Segmentation of brain immunohistochemistry images using clustering of linear centroids and regional shapes,”
Journal
of Imaging Science & Technology, vol.52, No.4, pp.040502-040502-11,
July/August, 2008.
[57]. M.I.Fiel , B.Sauter, H.-S. Wu, G. Rodriguez-Laiz, G.Gondolesi, K.Iyer, and T.D.Schiano,
“Regression of hepatic fibrosis after intestinal transplantation in patients with total parenteral nutrition liver disease,”
Clin. Gastroenterol Hepatol., vol.6, No.8, pp.926-933, 2008.
[56]. Hai-Shan Wu, Maria I. Fiel, T.D. Schiano, and Joan Gil,
“Image segmentation of liver fibrosis,”
Journal of Microscopy, vol.231, Pt.1, pp.70–80, 2008.
[55]. Masayuki Fukata, Anli Chen, Arunan
Vamadevan, Ruliang Xu, Hai-Shan Wu and Maria T. Abreu,
Crypt height represents intestinal mucosal barrier function during acute colitis: Correlation with epithelial cell proliferation and apoptosis, in:
Image Analysis in Medical Microscopy and Pathology, (H.-S.Wu & A.J.Einstein, ed.), Signpost, Kerala, pp.107-122, 2007.
[54]. Hai-Shan Wu, Sacha P. Salzberg, and Joan Gil,
“Automatic image segmentation with linear clustering for quantification of neo-intimal formation after surgical vein grafting,” Analytical & Quantitative Cytology Histology, vol.28, No.6, pp. 307-315, Dec. 2006.
[53]. Hai-Shan Wu, Veneta Hanson, and Joan Gil,
“Estimation of cell count from cell culture images,”
Journal of Imaging Science & Technology, vol.50, pp. 187-192, March/April
2006.
[52]. H.-S. Wu, and J. Gil,
“A biased median filtering algorithm for segmentation of
intestinal cell gland images,”
The Scientific World Journal, vol.6, pp.200–220, Feb. 2006.
[51]. Hai-Shan Wu, Ruliang Xu, Noam Harpaz, David Burstein,
and Joan Gil,
“Segmentation of intestinal gland images with iterative
region growing,”
Journal of Microscopy,
vol. 220, Pt 3, pp.190–204, Dec. 2005.
[50]. Hai-Shan Wu, Andrew J. Einstein, Tamara Kalir, Liane
Deligdisch, Noam Harpaz, David Burstein, and Joan Gil,
“Image analysis and morphometry in the diagnosis of cancer
cells: a review,” in:
Recent Research Developments in Cancer, pp.127-160, 2005.
[49]. Hai-Shan Wu, Ruliang Xu, Noam Harpaz, David Burstein,
and Joan Gil,
“Segmentation of microscopic images of small intestinal
glands with directional 2-D filters,”
Analytical & Quantitative Cytology Histology, vol.27, pp.291-300, No.5, Oct. 2005.
[48]. E.N.Schachter, G.Skloot, A.Chiarelli, J.Jose, H.Wu,
J.Gil, U.Arumugam, S.Bashir, N.Rienzi,
“Early Versus Late Effects of an Anti-Inflammatory Agent in
an Asthma Model,”
Amer. J. Respir. Crit. Care Med., vol. 171:A80,
2005.
[47]. Bitar M, Wu H-S, Szporn A, Burstein D, Gil J.
“Fast computerized texture analysis in pancreas cytology without accurate nuclear segmentation,”
Mod. Pathol., 18, supplement 1:326A, 2005.
[46]. L.D. Biertho, C. Kim, H.-S. Wu, P. Unger, and W. B. Inabnet,
“Relationship Between Sestamibi Uptake, Parathyroid Hormone
Assay and Nuclear Morphology in Primary Hyperparathyroidism,”
Journal of American College of Surgeons, vol.199,
No.2, pp.229-233, Aug. 2004.
[45]. Hai-Shan Wu, Liane
Deligdisch and Joan Gil,
“Segmentation of
microscopic nuclear images-A review,” in:
Recent Res. Devel.
Electr., vol.2, ISBN: 81-7895-151-7,
Transworld Research Publishing, Kerala, pp.1-18, 2004.
[44]. Hai-Shan Wu, Joan Gil, Liane Deligdisch, and Tamara Kalir,
“Characterization of ovarian nuclei with the parameter of power ratio,”
Microsc. Res. Tech., vol.64, No.4,
pp.287-292, 2004.
[43]. H.-S. Wu, A. J.
Einstein, L. Deligdisch, T. Kalir, and J. Gil,
“Characterization
of nuclear images based on analysis of fractional summation systems,”
Fractals,
vol.12, No.2, pp.157-169, 2004.
[42]. H.-S. Wu, J. Gil,
and L. Deligdisch,
"Region growing
segmentation of chromatin clumps of ovarian cells using adaptive
gradients,"
Journal of Imaging
Science & Technology, vol.48, No.1, pp.22-27, Jan./Feb. 2004.
[41]. J.Gil, and H.-S.
Wu,
"Applications of
image analysis to anatomic pathology: realities and promises,"
Cancer Investigation, vol.21, pp.950-959,
2003.
[40]. L.Deligdisch,
C.Miranda, H.-S.Wu, and J.Gil,
"Human
papillomavirus-related cervical lesions in adolescents: a histologic and
morphometric study,"
Gynecologic Oncology, vol.89, pp.52-59,
2003.
[39]. H.-S. Wu, and J.
Gil,
"Linear Clustering
for Segmentation of Color Microscopic Lung Cell Images,"
Journal of Imaging
Science & Technology, vol.47, pp.161-170, Mar./Apr. 2003.
[38]. J.Gil, H.-S.Wu,
and B.Wang,
"Image analysis
and morphometry in the diagnosis of breast cancer,"
Micros. Res. Tech., vol.59, pp.109-118,
Oct. 2002.
[37]. A.Butler, X.He,
R.E.Gordon, H.-S. Wu, S.Gatt, and E.H.Schuchman,
"Reproductive
pathology and sperm physiology in acid sphingomyelinase-deficient mice,"
American Journal of
Pathology, vol.161, No.3, pp.1061-1075, Sept. 2002.
[36]. D.N.Jourdy, G.S.Skloot, J.Gil, H.Wu, E.N.Schachter,
“The effect of chronic antigen challenge on airway smooth
muscle stretch induced relaxation,”
Am. J. Resp. Crit. Care. Med., vol.165, A255, 2002.
[35] A.J.Einstein,
H.-S. Wu, and J.Gil,
"Detrended
fluctuation analysis of chromatin texture for diagnosis in breast
cytology,"
Fractals, vol.10, No.1,
pp.19-25, March 2002.
[34] T. Kalir, H. Wu,
R. Gordon, and J.Gil,
"Morphometric and
electron microscopic analyses of the effect of gonadotropin-releasing hormone agonist
treatment on arteriole size in uterine leiomyomas,"
Arch. Pathol. Med., vol.124,
pp.1295-1298, Sept. 2000.
[33]. H.-S.Wu, J.Barba,
and J.Gil,
"Iterative
thresholding for segmentation of cell images,"
Journal of Microscopy, vol. 197, Pt.3, pp.296-304,
March 2000.
[32] L.Deligdisch,
J.Gil, H.Kerner, H.S.Wu, D.Beck, and R.Gershoni-Baruch,
"Ovarian dysplasia
in prophylactic oophorectomy specimens,"
Cancer, vol.86, pp.1544-1550,
Oct. 1999.
[31]. H.-S.Wu, J.Gil,
R. Jeremiah, and J.Barba,
"Unsupervised
learning for segmentation of textured cytologic images,"
IEE Electr. Lett., vol.35, No.8,
pp.630-631, Apr. 1999.
[30]. A.J.Einstein,
H.-S.Wu, and J.Gil,
Fractal
characterization of chromatin appearance for diagnosis in breast
cytology,"
Journal of Pathology, vol.185, pp.366-381,
Aug. 1998
[29]. T.Kalir,
M.Goldstein, P.Dottino, M.Brodman, P.Gordon, L.Deligdich, H.Wu, and J.Joan,
"Morphometric and
elctron-microscopic analysis of the effects of gonadotropin-releasing hormone
agonists on uterine leiomyomas,"
Arch. Pathol. Lab. Med., vol.122, pp.442-446,
May 1998.
[28]. H.-S.Wu, and
J.Barba,
"Minimum entropy
restoration of star field images,"
IEEE Transactions on
Systems, Man, and Cybernetics, vol.28, part B, No.2, pp.227-231, April 1998.
[27]. H.-S.Wu, J.Barba,
and J.Gil,
"A parametric
fitting algorithm for segmentation of cell images,"
IEEE Transactions on
Biomedical Engineering, vol.45, No.3, pp.400-407, Mar. 1998.
[26]. H.-S.Wu, J.Gil,
and J.Barba, "Optimal segmentation of cell images,"
IEE Proceedings,
Vision, Image and Signal Processing, vol.145, No.1, pp.50-56, Feb. 1998.
[25].
A.J.Einstein, H.-S.Wu, and J.Gil,
"Self-affinity
and lacunarity of chromatin texture in benign and malignant breast epithelial
cell,"
Physical
Rev. Lett., vol.80, pp.397-400, Jan. 1998.
[24]. A.J.Einstein,
H.-S.Wu, and J.Gil,
Fractal
characterization of nuclear texture in breast cytology: frequency and spatial
domain approaches, in:
Fractals in Biology and
Medicine
(G.Losa ed.), Nov. 1997.
[23]. H.-S.Wu,
A.J.Einstein, and J.Gil,
"Fractal
characterization of irregularly shaped images by frequency analysis,"
Fractals, vol.5, No.4,
pp.665-672, Dec. 1997.
[22]. A.J.Einstein, J.Gil,
S.Wallenstein, C.A.Bodian, M.Sanchez, D.E.Burstein, C.Sheppard, H.-S.Wu, and
Z.Liu,
"The
reproducibility of interactive segmentation procedures for breast
cytology,"
Journal of Microscopy, vol.188, Pt.2,
pp.136-148, Nov. 1997.
[21]. H.-S.Wu, R.A.King,
J.Barba, and J.Gil,
"DCT basis
decomposition coding for biomedical X-ray images using vector
quantization,"
Journal of Imaging
Science and Technology, vol.41, pp.160-167, March 1997.
[20]. H.-S.Wu, and
J.Barba, J.Gil,
"A focusing
algorithm for high magnification cell imaging,"
Journal of Microscopy, vol.184, pt.2,
pp.133-142, Nov. 1996.
[19]. H.-S.Wu, and
J.Barba, J.Gil,
"An iterative
algorithm for cell segmentation using short-time Fourier transform,"
Journal of Microscopy, vol.184, pt.2,
pp.127-132, Nov. 1996.
[18].
H.-S.Wu, and J.Barba, J.Gil,
"Region
growing segmentation of textured cell images,"
IEE Electr. Lett., vol.32,
pp.1084-1085, June 1996.
[17]. H.-S.Wu, J.Barba,
and J.Gil,
"Morphological
segmentation of textured cell images,"
Journal of Imaging
Science and Technology, vol.40, pp.265-270, May 1996.
[16]. H.-S.Wu, and
J.Barba,
"An efficient
semi-automatic algorithm for cell contour extraction,"
Journal of Microscopy, vol.179, pt.3,
pp.270-276, Sept. 1995.
[15]. H.-S.Wu, and
J.Barba,
"A classified
algorithm for segmentation of multispectral images,"
Journal of Imaging
Science and Technology, vol.39, pp.26-30, Jan. 1995.
[14]. J.Xia, F.Qi, W.Yuan, D.Wang, W.Qiu, Y.Sun, Y.Huang, G.Shen, H.Wu, "Computer Aided Simulation System for Orthognathic Surgery," Proc. IEEE Symp. Computer-Based Medical Systems, pp.237-240, 1995.
[13]. H.-S.Wu, and
J.Barba,
"An Algorithm for
Noisy Cell Contour Extraction via Area Merging,"
Journal of Imaging
Science and Technology, vol.38, pp.604-607, Nov 1994.
[12]. H.-S.Wu, and
J.Barba,
"Coding of
quadtree structure using run-length code,"
IEE Electr. Lett., vol.29,
pp.1741-1742, Sept. 1993.
[11]. H.-S.Wu,
"Minimum entropy
deconvolution of images,"
Journal of China
Institute of Communications, vol.14, No.4, pp.88-94, July 1993.
[10]. H.-S.Wu, and J.Barba,
"Index allocation
in vector quantization for noisy channels,"
IEE Electr. Lett., vol.29,
pp.1317-1319, July 1993.
[9]. H.-S.Wu, R.A.King
and R.I.Kitney,
"Improving the
performance of the quadtree-based image approximation via the generalized
DCT,"
IEE Electr. Lett., vol.29, pp.887-888,
May 1993.
[8]. F.-H.Qi, and
H.-S.Wu,
"Real-time image
filtering using the pipelines,"
Journal of Infrared and
Millimeter Waves, vol.12, pp.52-56, Feb. 1993.
[7]. H.-S.Wu, and X.H.Gu,
"Hexagonal
discrete coding transform image coding,"
Journal of Shanghai
Jiaotong University, vol.27, No.1, pp.80-87, Jan. 1993.
[6]. K.Xin, and
H.-S.Wu,
"Low-rate interpolation
image coding,"
Journal of Shanghai
Jiaotong University, vol.26, No.3, pp.10-16, May 1992.
[5]. H.-S.Wu,
"Blind image
restoration for zero-phase blurs,"
Journal of Imaging
Science and Technology, vol.36, pp.206-208, Mar. 1992.
[4]. H.-S.Wu,
"A fast search
algorithm for vector quantization,"
IEE Electr. Lett., vol.28, pp.457-458,
Feb. 1992.
[3]. H.-S.Wu,
"Hexagonal
discrete cosine transform for image coding,"
IEE Electr. Lett., vol.27, pp.781-783,
Apr.1991.
[2]. H.-S.Wu,
"Minimum entropy
deconvolution for restoration of blurred two-tone images,"
IEE Electr. Lett., vol.26,
pp.1183-1184, July 1990.
[1]. F.-N.Ku, and
H.-S.Wu,
"Edge detection
with a filter concentrating the energy,"
Journal of China
Institute of Communications, vol.7, pp.85-91, Nov.1986.
Books:
[1]. Hai-Shan
Wu & Andrew Einstein, (ed.),
Image Analysis in Medical Microscopy and Pathology,
Signpost, Kerala, 2007.
